On May 2, 2025, the Centers for Disease Control reported twelve pediatric deaths associated with seasonal influenza virus infection in the current week, bringing the 2024-2025 season total to 216 pediatric deaths.

This number of pediatric deaths exceeds the previous high reported for a regular (non-pandemic) season. The previous high of 207 was reported during the 2023-2024 season.

The CDC estimates that there have been at least 47 million illnesses, 610,000 hospitalizations, and 26,000 deaths from flu so far this season. CDC continues to recommend that everyone ages 6 months and older get an annual flu vaccine as long as influenza viruses are circulating.

There are prescription flu antiviral drugs that can treat flu illness; those should be started as early as possible and are especially important for patients at higher risk for severe illness.

Based on data from FluSurv-NET, the cumulative hospitalization rate for this season is the highest observed since the 2010-2011 season.