In 1983, Computerized tomography of the colon (virtual colonoscopy) was proposed as a screening method to identify colon polyps and colorectal cancer.

Over a decade later, in 1994, the term “virtual colonoscopy” was formally introduced. Since then, great advances in software and hardware have occurred. Clinical studies began to include more patients, better technologies were developed, and improved techniques were used.

In 1996, a small study was conducted to determine the optimal CTC scanning parameters based on an artificial colon model and to determine the feasibility of using CTC in a clinical setting by using optical colonoscopy as the reference standard.

Since 1996, studies have been conducted using multiple scanning parameters, different risk populations, multiple stool and fluid tagging techniques, multiple colon preparation techniques, different image processing techniques, and differing radiologist experience with CTC to determine the best technique for screening. Recent advancements in CTC include new reconstruction techniques and advanced image processing.

The American Cancer Society estimates that 90% of CRC cases and deaths are preventable with regular CRC screening. It has been recommended that an average-risk person begin screening at age 50.