Har Gobind Khorana won a share of the Nobel Prize in Physiology or Medicine for his work in genetics and protein synthesis

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In 1968, Har Gobind Khorana won a share of the Nobel Prize in Physiology or Medicine for his work in genetics and protein synthesis.

In the 1950s, it was established that genetic information is transferred from DNA to RNA, to protein. One sequence of three nucleotides in DNA corresponds to a certain amino acid within a protein. How could this genetic code be cracked? After Marshall Nirenberg discovered the first piece of the puzzle, the remainder of the code was gradually revealed in the years that followed.

Har Gobind Khorana made important contributions to this field by building different RNA chains with the help of enzymes. Using these enzymes, he was able to produce proteins. The amino acid sequences of these proteins then solved the rest of the puzzle.n a share of the Nobel Prize in Physiology or Medicine for his work in genetics and protein synthesis.

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Source: Nobel Prize
Credit: Photo: Har Gobind Khorana, courtesy the Nobel Foundation.