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Daily statin reduced the risk of cardiovascular disease in people living with HIV, large NIH study found
Biotechnology | Disease | HIV | NIH | Non-Profit Research

Daily statin reduced the risk of cardiovascular disease in people living with HIV, large NIH study found

On Apr. 11, 2023, a National Institutes of Health (NIH) clinical trial was stopped early because a daily…

Read More Daily statin reduced the risk of cardiovascular disease in people living with HIV, large NIH study foundContinue

Experimental HIV vaccine regimen safe but ineffective, study found
Biotechnology | HIV | NIH | Vaccine

Experimental HIV vaccine regimen safe but ineffective, study found

On Jan. 18, 2023, the National Institutes of Health (NIH) announced that an investigational HIV vaccine regimen tested…

Read More Experimental HIV vaccine regimen safe but ineffective, study foundContinue

Moderna announced mRNA-1345, an investigational RSV Vaccine, met primary efficacy endpoints in phase 3 trial
Biotechnology | COVID-19 | Infectious Disease | Vaccine

Moderna announced mRNA-1345, an investigational RSV Vaccine, met primary efficacy endpoints in phase 3 trial

On Jan. 17, 2023, Moderna announced positive topline data from its ConquerRSV Phase 3 pivotal efficacy trial of…

Read More Moderna announced mRNA-1345, an investigational RSV Vaccine, met primary efficacy endpoints in phase 3 trialContinue

Relief reports that its U.S. collaboration partner announced DSMB recommended termination of ACTIV-3b study in critical COVID-19
Life Science History

Relief reports that its U.S. collaboration partner announced DSMB recommended termination of ACTIV-3b study in critical COVID-19

On May 26, 2022, RELIEF THERAPEUTICS announced that the parent company, NRx Pharmaceuticals, of its collaboration partner with…

Read More Relief reports that its U.S. collaboration partner announced DSMB recommended termination of ACTIV-3b study in critical COVID-19Continue

CureVac provided update on phase 2b/3 trial of first-generation COVID-19 vaccine candidate, CVnCoV
COVID-19 | Life Science History | Vaccine

CureVac provided update on phase 2b/3 trial of first-generation COVID-19 vaccine candidate, CVnCoV

On Jun. 16, 2021, CureVac announced results of the second interim analysis of its international pivotal Phase 2b/3…

Read More CureVac provided update on phase 2b/3 trial of first-generation COVID-19 vaccine candidate, CVnCoVContinue

DSMB confirmed CureVac pivotal phase 2b/3 study for first-generation COVID-19 vaccine candidate
COVID-19 | Life Science History | Vaccine

DSMB confirmed CureVac pivotal phase 2b/3 study for first-generation COVID-19 vaccine candidate

On May 28, 2021, CureVac announced that the independent Data Safety Monitoring Board (DSMB)confirmed that the pivotal Phase…

Read More DSMB confirmed CureVac pivotal phase 2b/3 study for first-generation COVID-19 vaccine candidateContinue

Investigational AstraZeneca vaccine prevented COVID-19
COVID-19 | Life Science History | NIH | Vaccine

Investigational AstraZeneca vaccine prevented COVID-19

On Mar. 22, 2021, the NIH announced that results from a large clinical trial in the U.S. and…

Read More Investigational AstraZeneca vaccine prevented COVID-19Continue

Abivax stopped phase 2b/3 miR-AGE Covid-19 clinical trial due to lack of efficacy
Life Science History

Abivax stopped phase 2b/3 miR-AGE Covid-19 clinical trial due to lack of efficacy

On Mar. 5, 2021, Abivax announced tthat it was halting the miR-AGE phase 2b/3 clinical trial in high-risk…

Read More Abivax stopped phase 2b/3 miR-AGE Covid-19 clinical trial due to lack of efficacyContinue

NIH-sponsored ACTIV-3 clinical trial closed enrollment into two sub-studies
COVID-19 | Life Science History | NIH

NIH-sponsored ACTIV-3 clinical trial closed enrollment into two sub-studies

On Mar. 4, 2021, the NIH announced that the ACTIV-3 clinical trial evaluating the safety and efficacy of…

Read More NIH-sponsored ACTIV-3 clinical trial closed enrollment into two sub-studiesContinue

RedHill’s phase 2/3 COVID-19 study of opaganib passed second DSMB with unanimous recommendation
Biotechnology | COVID-19 | Pharmaceutical | Therapeutics

RedHill’s phase 2/3 COVID-19 study of opaganib passed second DSMB with unanimous recommendation

On Dec. 22, 2020, RedHill Biopharma announced that the global Phase 2/3 study with orally-administered opaganib (Yeliva, ABC294640)1…

Read More RedHill’s phase 2/3 COVID-19 study of opaganib passed second DSMB with unanimous recommendationContinue

Moderna received FDA Advisory Committee vote supporting EUA for vaccine against COVID-19 in the U.S.
Biotechnology | COVID-19 | FDA | Vaccine

Moderna received FDA Advisory Committee vote supporting EUA for vaccine against COVID-19 in the U.S.

On Dec. 17, 2020, Moderna confirmed that the U.S. Food and Drug Administration’s (FDA) Vaccines and Related Biological…

Read More Moderna received FDA Advisory Committee vote supporting EUA for vaccine against COVID-19 in the U.S.Continue

Moderna announced primary efficacy analysis in phase 3 COVE study for COVID-19 vaccine candidate
Biotechnology | Diagnostics | FDA | Infectious Disease | Vaccine

Moderna announced primary efficacy analysis in phase 3 COVE study for COVID-19 vaccine candidate

On Nov. 30, 2020, Moderna announced that the primary efficacy analysis of the Phase 3 study of mRNA-1273…

Read More Moderna announced primary efficacy analysis in phase 3 COVE study for COVID-19 vaccine candidateContinue

Moderna amended supply agreement with UK Government for 2 million doses of mRNA COVID-19 vaccine
Biotechnology | COVID-19 | Infectious Disease | Vaccine

Moderna amended supply agreement with UK Government for 2 million doses of mRNA COVID-19 vaccine

On Nov. 29, 2020, Moderna announced a supply agreement with the United Kingdom (UK) government for an additional…

Read More Moderna amended supply agreement with UK Government for 2 million doses of mRNA COVID-19 vaccineContinue

Moderna’s COVID-19 vaccine candidate met primary endpoint in first interim analysis of phase 3 COVE study
Biotechnology | COVID-19 | Infectious Disease | Life Science History | NIH | Vaccine

Moderna’s COVID-19 vaccine candidate met primary endpoint in first interim analysis of phase 3 COVE study

On Nov. 15, 2020, an independent data and safety monitoring board (DSMB) overseeing the Phase 3 trial of…

Read More Moderna’s COVID-19 vaccine candidate met primary endpoint in first interim analysis of phase 3 COVE studyContinue

DSMB analysis recommended continuance of P3 COVID-19 ARDS trial
Biotechnology | COVID-19 | Therapeutics

DSMB analysis recommended continuance of P3 COVID-19 ARDS trial

On Nov. 11, 2020, Mesoblast announced that the randomized controlled Phase 3 trial of remestemcel-L in patients with…

Read More DSMB analysis recommended continuance of P3 COVID-19 ARDS trialContinue

Johnson & Johnson temporarily paused all dosing in Janssen COVID-19 vaccine candidate clinical trials
COVID-19 | Life Science History | Vaccine

Johnson & Johnson temporarily paused all dosing in Janssen COVID-19 vaccine candidate clinical trials

On Oct. 12, 2020, Johnson & Johnson announced temporarily paused further dosing in all our COVID-19 vaccine candidate…

Read More Johnson & Johnson temporarily paused all dosing in Janssen COVID-19 vaccine candidate clinical trialsContinue

Humanigen announced review of lenzilumab phase 3 study in COVID-19 by Data Safety Monitoring Board
COVID-19 | Life Science History

Humanigen announced review of lenzilumab phase 3 study in COVID-19 by Data Safety Monitoring Board

On Sept. 14, 2020, Humanigen announced its Phase 3 registration trial of lenzilumab in patients with COVID-19 was…

Read More Humanigen announced review of lenzilumab phase 3 study in COVID-19 by Data Safety Monitoring BoardContinue

The NIH halted clinical trial of hydroxychloroquine
Biotechnology | COVID-19 | Infectious Disease | NIH | Therapeutics

The NIH halted clinical trial of hydroxychloroquine

On Jun. 20, 2020, the National Institutes of Health (NIH) announced that a clinical trial to evaluate the…

Read More The NIH halted clinical trial of hydroxychloroquineContinue

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