European Commission approved first CRISPR/Cas9 gene-edited therapy, CASGEVY for reatment of SCD and TDT
On Feb. 13, 2024, CRISPR Therapeutics announced that the European Commission had granted conditional marketing authorization to CASGEVY…
bluebird bio announced commercial launch of LYFGENIA’ gene therapy for patients ages 12 and older with sickle cell disease
On Dec. 8, 2023, bluebird bio announced the U.S. commercial launch of its LYFGENIA’ (lovotibeglogene autotemcel, also known…
Biotechnology | CRISPR | FDA | Genomics | Therapeutics
Vertex and CRISPR Therapeutics announced U.S. FDA approval of CASGEVY for treatment of sickle Cell disease
On Dec. 8, 2023, Vertex Pharmaceuticals and CRISPR Therapeutics announced that the U.S. Food and Drug Administration (FDA)…
CRISPR | Genomics | Stem Cell | Therapeutics
FDA approved first gene therapies to treat patients with sickle cell disease
On Dec. 8, 2023, the U.S. Food and Drug Administration approved two milestone treatments, Casgevy and Lyfgenia, representing…
Vertex and CRISPR Therapeutics announced authorization of first CRISPR/Cas9 gene-edited therapy by UK MHRA for treatment of Sickle Cell Disease
On Nov. 16, 2023, Vertex and CRISPR Therapeutics announced that the United Kingdom (U.K.) Medicines and Healthcare products…
Biotechnology | Cartoons - Original | CRISPR | Disease | Genomics | Life Science History | Therapeutics
Milestones in CRISPR
Our Milestones in CRISPR cartoon illustrates several significant achievements in the development of the technology with commentary by…
Biotechnology | Cartoons - Original | CRISPR | Disease | Genomics | Life Science History | Therapeutics | U.S. Congress | Vaccine
U.S. Biotechnology & Biomanufacturing Initiative
On Sept. 14, 2022, The U.S. Biotech Initiative was announced detailing new investments and resources to advance the…
Biotechnology | Cartoons - Original | CRISPR | Disease | Genomics | Life Science History | Therapeutics
Evolution of CRISPR
The Evolution of CRISPR illustrates its climb out of the primordial ocean on the backs of eukaryotic cells…
Novartis and Gates Foundation collaborate to discover and develop in vivo gene therapy for sickle cell disease
On Feb. 17, 2021, Novartis announced that it had entered into a grant agreement with the Bill &…
Biotechnology | CRISPR | FDA | Therapeutics
FDA cleared initiation of the Editas Medicine’s EDIT-301 clinical trial using CRISPR/Cas12a gene editing
On Jan. 11, 2021, Editas Medicine announced the U.S. Food and Drug Administration (FDA) had cleared the initiation…
Biotechnology | CRISPR | FDA | Therapeutics
CIRM-funded project targeting sickle cell disease received green light for clinical trial
On Dec.14, 2020, the US Food and Drug Administration (FDA) announced they had granted Investigational New Drug (IND)…
CIRM board approved clinical trials targeting COVID-19 and sickle cell disease
On May 15, 2020, the California Institute for Regenerative Medicine (CIRM) board approved new clinical trials for COVID-19…
NIH announced $1 million prize competition to target global disease diagnostics
On Feb. 25, 2020, the U. S. National Institutes of Health (NIH) announced it had launched a $1…
FDA approved new sickle cell treatment based on clincal trial resutls from UTHSC’s Kenneth Ataga, MD
On Dec. 2, 2019, the U.S. Food and Drug Administration (FDA) announced it had approved the drug crizanlizumab…
First use of CRISPR tool to successfully treat patient with genetic disorder
On Jul. 19, 2019, Victoria Gray, 34, of Forest, Miss., became the first patient ever to be publicly…
The FDA approved Endari developed by Dr Yutaka Niihara at LA Biomed
On Jun. 7, 2017 the FDA approved Endari (L-glutamine oral powder) for patients age five years and older…
St. ﾠJude Children’s Research Hospital received NCI comprehensive center designation
In 2008, the St.ﾠ Jude Children’s Research Hospital received National Cancer Institute (NCI) comprehensive center designation. St.ﾠJude Children’s…
Karmanos Institute and JP McCarthy Cord Stem Cell Bank founded
In 2001, The J.P. McCarthy Cord Stem Cell Bank at the Karmanos Cancer Institute was founded as a…
Francisco Mojica characterized CRISPR
On Aug. 9, 1993, Francisco Mojica published “Transcription at different salinities of Haloferax mediterranei sequences adjacent to partially…
Medical College of Georgia researchers identified transcranial Doppler as first noninvasive method to identify children with sickle cell disease at risk for stroke
On Feb. 27, 1992, Dr. Robert Adams and Dr. Virgil C. McKie of the Medical College of Georgia…
Biotechnology | CRISPR | Diagnostics | Disease | NIH | Therapeutics
Dr. Marilyn Hughes Gaston published groundbreaking study that led to a national sickle cell disease screening program
In 1986, Dr. Marilyn Hughes Gaston while deputy branch chief of the Sickle Cell Disease Branch at the…
Sickle Cell Disease Awareness Month was Established
On Sept. 21, 1983, Sickle Cell Month was officially recognized nationally when the U.S. House of Representatives unanimously…
Stﾠ. Jude Children’s Research Hospital received NCI designation
In 1977, St.ﾠ Jude Children’s Research Hospital received National Cancer Institute designation. St.ﾠJude Children’s Research Hospital opened it’s…
Sickle Cell Disease Awareness Month originated
In 1975, Sickle Cell Disease Awareness Month originated when the Sickle Cell Disease Association of America and its…
Stﾠ. Jude Children’s Research Hospital was founded
On Feb. 4, 1962, St.ﾠ Jude Children’s Research Hospital opened it’s doors.This was the day that Danny Thomas…
The first documented case of sickle cell disease, with full autopsy findings, was published at Medical College of Georgia
In 1923, Dr. Virgil P. Sydenstricker published the first documented case of sickle cell disease, with full autopsy…