In 1982, The Whitehead Institute, was founded as an independent research institution affiliated with Massachusetts Institute of Technology (MIT) through the efforts of Edwin C. “Jack” Whitehead pioneer of the modern clinical diagnostics industry.

From 1982-84, Jack Whitehead provided $35 million to build and equip the new Whitehead building, as well as $5 million per year in guaranteed income and a substantial endowment in his will. At the time, the total gift was valued at $135 million.