On May 27, 2025, the Arizona Department of Agriculture (AZDA) reported that poultry at a second commercial farm located in Maricopa County tested positive for Avian Influenza. When the poultry began showing clinical signs consistent with avian influenza on May 21, 2025, samples from the location were submitted to the Arizona Veterinary Diagnostic Lab (AZVDL) for preliminary determination, then submitted to the National Veterinary ServicesLaboratory (NVSL) for confirmation, received on May 27.

Eggs produced after the onset of clinical signs of illness have not entered the food supply, and there were no signs of illness in humans. The Arizona Department of Agriculture (AZDA) engaged with the USDA, Arizona Department of Health Services, Arizona Department of Environmental Quality, Arizona Department of Emergency and Military Affairs, and Maricopa County Department of Public Health to ensure a quick and appropriate response to addressing this animal disease emergency

The affected poultry farm was placed under quarantine on the recommendation of the Director of the AZDA and the AZDA State Veterinarian. Enhanced biosecurity measures were in place and efforts were underway to perform virus elimination. All applicable sanitation responses were quickly implemented.