Six COVID-19 patients treated with RedHills opaganib under compassionate use show objective clinical improvement
On Apr. 27, 2020, RedHill Biopharma provided an additional update on the compassionate use program with its investigational…
Biotechnology | COVID-19 | FDA | Therapeutics
Mateon announced filing of IND with FDA to evaluate antisense drug candidate OT-101 in COVID-19 patients
On Apr. 27, 2020, Mateon Therapeutics announced announced it has submitted an Investigational New Drug application to the…
Neurocrine Biosciences announced FDA approval of ONGENTYS as treatment for patients with Parkinson’s Disease
On Apr. 27, 2020, Neurocrine Biosciences announced the FDA approved once-daily oral ONGENTYS (opicapone) 25 mg and 50…
Edwards HemoSphere platform receives expanded use indication from Health Canada in treatment of COVID-19 patients
On Apr. 27, 2020, Edwards Lifesciences announced that Health Canada approved an expanded indication for use of the…
BioAegis demonstrated Gelsolin therapy can quell the cytokine storm and promote tissue repair
On Apr. 27, 2020, BioAegis Therapeutics announced it had published gene expression data in animal studies where recombinant…
Regeneron and Sanofi updated phase 2/3 adaptive-designed trial of Kevzara (sarilumab) in hospitalized COVID-19 patients
On Apr. 27, 2020, Regeneron and Sanofi announced preliminary results from the Phase 2 portion of an ongoing…
Phase 3 trial of Libtayo (cemiplimab) as monotherapy for first-line advanced non-small cell lung cancer stopped early due to highly significant improvement in overall survival
On Apr. 27, 2020, Regeneron and Sanofi announced the primary endpoint of overall survival was met in a…
iBio estimated 500 Million Dose Capacity for COVID-19 Vaccine from its FastPharming Facility
On Apr. 27, 2020, iBio announced it has joined the National Institute for Innovation in Manufacturing Biopharmaceuticals (NIIMBL),…
Merck and Institute for Systems Biology collaborate to define molecular mechanisms of SARS-CoV-2 infection and identify potential prognostic biomarkers
On Apr. 27, 2020, Merck and the Institute for Systems Biology announced a new research collaboration to investigate…
CTI Biopharma announced initiation of phase 3 PRE-VENT study evaluating Pacritinib in hospitalized patients with severe COVID-19
On Apr. 27, 2020, CTI BioPharma announced initiation of PRE-VENT, a Phase 3 study evaluating pacritinib in hospitalized…
Atossa Therapeutics contracted with NYC Health + Hospitals/Metropolitan for COVID-19 HOPE clinical study
On Apr. 27, 2020, Atossa Therapeutics announced that it had contracted with NYC Health + Hospitals/Metropolitan in New…
FDA warns of ‘Off-Label’ use of antimalarial drugs hydroxychloroquine and chloroquine to treat COVID-19 patients
On Apr. 24, 2020, the U.S. Food and Drug Administration (FDA) issued a Drug Safety Communication regarding known…
Mesoblast reported 83% survival in ventilator-dependent COVID-19 patients (10/12) with moderate/severe acute respiratory distress syndrome
On Apr. 24, 2020, Mesoblast announced an 83% survival in ventilator-dependent COVID-19 patients (10/12) with moderate/severe acute respiratory…
Global study to assess effects of COVID-19 in pregnancy on mothers and babies was launched
On Apr. 24, 2020, researchers at the University of Oxford announced the start of a large, international study…
CIRM Board funded first clinical study for COVID-19
On Apr. 24, 2020, the governing Board of the California Institute for Regenerative Medicine (CIRM) awarded $749,999 to…
Keck Foundation gifted $4 million to USC to speed public health and research on COVID-19
On Apr. 24, 2020, the W. M. Keck Foundation announced a $4 million gift that will help scientists…
ViralClear submits investigational New Drug Application to FDA for phase II clinical trials for merimepodib
On Apr. 24, 2020, BioSig Technologies announced that subsidiary ViralClear had submitted an Investigational New Drug (IND) application…
OHSU team designed low-cost ventilators using 3D-printing technology
On Apr. 24, 2020, Oregon Health & Science University (OHSU) announced that a research team led by Albert…
Oxford University COVID-19 vaccine began human trial stage
On Apr. 23, 2020, University of Oxford researchers announced they had begun testing a COVID-19 vaccine in human…
ViralClear published comparative in vitro data on merimepodib and remdesivir activity against COVID-19 novel Coronavirus in F1000 research
On Apr. 23, 2020, BioSig Technologies announced that an article titled, ‘The IMPDH inhibitor merimepodib has similar antiviral…
Emergent BioSolutions signed agreement to be U.S. manufacturing partner for Johnson & Johnson’s lead vaccine candidate for COVID-19
On Apr. 23, 2020, Emergent BioSolutions announced an agreement whereby Emergent will deploy its contract development and manufacturing…
CHF Solutions shipped first commercial orders of Aquadex SmartFlow system to Austria
On Apr. 23, 2020, CHF Solutions announced that it had shipped the first commercial orders of its next…
Mayo Clinic partnered with state of Minnesota, University of Minnesota on breakthrough COVID-19 initiative
On Apr. 23, 2020, the Mayo Clinic, Minnesota Department of Health and University of Minnesota announced a breakthrough…
Roswell Park and Partners announced new Western New York Immunogenomic COVID-19 Study
On Apr. 23, 2020, Western New York healthcare and medical research leaders joined forces in an effort to…
Biotechnology | Disease | FDA | Oncology | Therapeutics
The FDA approved new therapy for triple negative breast cancer
On Apr. 22, 2020, the U.S. Food and Drug Administration (FDA) granted accelerated approval to Trodelvy (sacituzumab govitecan-hziy),…
Tyson Foods indefinitely suspended operations in Waterloo, Iowa
On Apr. 22, 2020, Tyson Fresh Meats, the beef and pork subsidiary of Tyson Food, planned to indefinitely…
Researchers identified cells likely targeted by COVID-19 virus
On Apr. 22, 2020, researchers at Massachusetts Institute of Technology (MIT); the Ragon Institute of MGH, and Harvard…
Cocrystal Pharma expanded exclusive license agreement with Kansas State University Research Foundation to new Coronavirus antiviral compound
On Apr. 22, 2020, Cocrystal Pharma announced it has expanded its previously announced license agreement with Kansas State…
Expert U.S. panel developed NIH treatment guidelines for COVID-19
On Apr. 21, 2020, a panel of U.S. physicians, statisticians, and other experts developed treatment guidelines for coronavirus…
FDA approved IMBRUVICA (ibrutinib) plus Rituximab for ttreatment of patients with CLL
On Apr. 21, 2020, the Janssen Pharmaceutical Companies of Johnson & Johnson announced U.S. Food and Drug Administration…