The 4D nucleome project was started
In 2015, the 4D Nucleome Network was begun with the goal to develop and apply approaches to map…
Stanford scientists transformed mouse skin cells directly into functional nerve cells with the application of just three genes
On Jan. 27, 2010, scientists at the Stanford University School of Medicine announced they had succeeded in the…
Biotechnology | Diagnostics | Disease | Genomics | NIH | Oncology | Therapeutics
National Cancer Institute mouse studies identified gene that may influence metastasis risk in breast cancer
On Apr. 29, 2008, National Cancer Institute (NCI) researchers identified a pattern of gene activity in mice that…
The Allen Institute for Brain Science Completed the Brain Atlas
On Sept. 26, 2006, the Allen Institute for Brain Science announced the completion of the groundbreaking Allen Brain…
Biotechnology | FDA | Oncology | Therapeutics
The monoclonal antibody cetuximab (Erbitux) was approved by the FDA for the treatment of metastatic colorectal cancer
On Feb. 1, 2004, the U.S. Food and Drug Administration (FDA) announced it had approved Cetuximab, a recombinant…
The mouse genome was first sequenced and published
On Dec. 5, 2002, the international Mouse Genome Sequencing Consortium announced the publication of a high-quality draft sequence…
Peter St. George-Hyslop developed a vaccine that prevented Alzheimer’s disease in mice
On Dec. 21, 2000, Dr. Peter St George-Hyslop developed a vaccine that prevented Alzheimer’s disease in mice. The…
Stanford researchers discovered hereditary arthritis gene
On Jul. 11, 2000, Stanford researchers announced they had identified a substance commonly added to toothpaste to prevent…
Biotechnology | Diagnostics | Genomics | NIH | Therapeutics
Livermore National Lab work was completed on the mouse genome as part of Laboratory efforts in comparative genomics
On Oct. 30, 1999, Livermore National Lab work completed work on the mouse genome as part of Laboratory…
Mouse model of prostate cancer was developed at Washington University – St Louis
On Dec. 22, 1998, Washington University – St. Louis researcher Jeffrey I. Gordon, MD and colleagues developed a…
Mouse model of promyelocytic leukemia was developed at Washington University – St Louis
In 1997, a mouse model of promyelocytic leukemia was developed by Washington University – St. Louis researcher Timothy…
The first genetically engineered mouse model showing amyloid plaques was developed at the University of Minnesota
In 1996, the first genetically engineered mouse model showing amyloid plaques and dysfunctional learning and memory found in…
The CDC responded to a Hantavirus outbreak in the southwestern U.S.
In May 1993, the U.S. Centers for Disease Control and Prevention (CDC) responded to a Hantavirus outbreak in…
Stanford Medicine researchers developed an animal model for studying the human immune system
In 1988, Stanford Medicine researchers Irving Weissman and Mike McCune created an animal model that can be used…
The Harvard Mouse, created by molecular geneticists, becomes the first mammal patented in the U.S.
On Apr. 12, 1988, the Harvard Mouse created by molecular geneticists led by Philip Leder created the first…
Stanford Medicine researchers Isolated pure hematopoietic stem cells from mice
In 1988, pathologist Irving Weissman from Stanford Medicine isolated a rare mouse cell, known as the hematopoetic stem…
The ‘oncomouse’ was developed
In 1984, genetic scientists led by Philip Leder created the first genetically engineered mouse model of cancer, nicknamed…
University of Washington scientists created first “transgenic mouse”
In 1982, Richard D. Palmiter at the University of Washington scientists created first “transgenic mouse” in collaboration with…
The TP53 gene from the mouse was first cloned by Peter Chumakov of the Russian Academy of Sciences
In 1982, the TP53 gene from the mouse was first cloned by Peter Chumakov of the Russian Academy…
Researchers from the University of Pennsylvania and the University of Washington injected purified DNA into a single-cell mouse embryo
In 1981, Frank Ruddle from Yale University, Frank Costantini and Elizabeth Lacy from Oxford, and Ralph L. Brinster…
Biology | Diagnostics | Disease | Life Science History | NIH | Oncology | Radiology | Therapeutics | Women's Health
NCI scientists published first monograph that showed the mouse breast cancer “agent” was a filterable virus
In 1945, W. Ray Bryan, Michael B. Shimkin, Howard B. Andervont, Herbert Kahler and Thelma B. Dunn published…
Glenn H Algire demonstrated a method for making microscopic studies in vivo to view tumor growth in the mouse
In 1943, Glenn H. Algire, using the transparent-chamber technique, demonstrated a method for making microscopic studies in vivo…
Murray J. Shear coined the term “cocarcinogen”
In 1938, Murray J. Shear from the National Cancer Institute (NCI) reported that a basic fraction of creosote…
Margaret Pittman showed precipitin reaction around meningococcus colonies on immune serum was correlated with mouse potency assay
In 1938, Margaret Pittman showed that the precipitin reaction around meningococcus colonies on immune serum agar plates was…