ACIP recommended adoption of a sequential series of two doses of IPV followed by two doses of OPV for all infants and children

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In 1997, the Immunization Practices Advisory Committee (ACIP) recommended adoption of a sequential series of two doses of IPV followed by two doses of OPV for all infants and children to decrease the rare occurrences of Vaccine Associated Paralytic Polio (VAPP) that were noted following the administration of live oral poliovirus vaccine.

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